The Secret to Living to 100? It’s Not Good Habits
Good genes matter more the older you get
By ALEX JANIN
Fri, Oct 13, 2023 9:33am
4 min
4 min
If you want to live to your 100th birthday, healthy habits can only get you so far.
Research is making clearer the role that genes play in living to very old age. Habits like getting enough sleep, exercising and eating a healthy diet can help you stave off disease and live longer, yet when it comes to living beyond 90, genetics start to play a trump card, say researchers who study ageing.
“Some people have this idea: ‘If I do everything right, diet and exercise, I can live to be 150.’ And that’s really not correct,” says Robert Young, who directs a team of researchers at the nonprofit scientific organisation Gerontology Research Group.
About 25% of your ability to live to 90 is determined by genetics, says Dr. Thomas Perls, a professor of medicine at Boston University who leads the New England Centenarian Study, which has followed centenarians and their family members since 1995. By age 100, it’s roughly 50% genetic, he estimates, and by around 106, it’s 75%.
Knowing what enables some people to live very long lives has consequences for the rest of us. Ongoing research into very old age may help provide insight that could eventually be used to develop drugs or identify lifestyle changes to help people live healthier for longer, says Dr. James Kirkland, president of the American Federation for Aging Research.
Who makes it to 100
Centenarians make up a growing share of the U.S. population. There are about 109,000 centenarians living in the country in 2023, according to Census Bureau projections, up from about 65,000 10 years ago, thanks in part to decades of advances in medicine and public health.
Despite a decline in life expectancy, which dropped to 76.4 in 2021, Perls estimates that roughly 20% of the population has the genetic makeup that could get them to 100 if they also make consistent healthy choices.
Not only do centenarians live longer, but data suggest they manage to avoid or delay age-related diseases like cancer, dementia and cardiovascular disease longer than the general population. Among the New England Centenarian Study participants, 15% are “escapers,” or people with no demonstrable disease at the age of 100; some 43% are “delayers,” those who didn’t develop age-related disease until age 80 or after.
Chuck Ullman, who is 97 and lives in a retirement community in Thousand Oaks, Calif., says he is free of health problems—aside from a sore right shoulder from a recent electric biking accident—and has no desire to live to a particular age. He hopes to live as long as he feels good and can do the things he loves, such as woodworking, attending political discussion groups and getting dinner with some of his many friends.
“There are 350 residents here, and I have 350 friends,” Ullman says of his community. He also spends time with Betty, his wife of 77 years. “My objective is to enjoy each and every day that comes along.”
Genes that matter
Researchers have identified some genes and combinations of them that are associated with longevity, such as the presence of a variant of what’s known as the apolipoprotein E gene called e2, a trait thought to help protect against Alzheimer’s. They emphasise each trait is a small piece in a large, complicated puzzle, which can factor in socioeconomic status, race and ethnicity, and climate.
Living past 100 requires a combination of many genetic variants, each with a relatively modest effect, says Perls of the New England Centenarian Study.
Gene variants that offer protective qualities, such as repairing DNA damage, are especially beneficial, he says.
People who are curious about how long they might live should start by looking at their family histories. Your relatives’ lifespans are one of the strongest predictors of longevity, says Perls. Ullman, the 97-year-old, says his mother lived to 90.
If multiple members of your family have lived into very advanced age, “you’ve potentially won a much greater chance of having purchased the right lottery ticket,” says Perls.
Good habits
Neurologist Dr. Claudia Kawas has been tracking the habits of the “oldest old,” those older than 90, in Southern California since 2003, as part of a study at the University of California, Irvine. She and a team of researchers have found links between longevity and even short amounts of exercise, social activities such as going to church, and modest caffeine and alcohol intake.
“Super-agers,” or people over the age of 80 whose cognitive abilities are on par with those 20 to 30 years younger, reported having more warm, trusting, high-quality relationships with other people than cognitively normal participants, investigators at Northwestern University found.
“Keeping in good relationships could be one key to healthspan,” says Amanda Cook Maher, a neuropsychologist at the University of Michigan and lead author of the study.
Your outlook also matters. Harvard researchers identified a link between optimism and longer lifespans in women across racial and ethnic groups. Among the study participants, the 25% who were the most optimistic had a greater likelihood of living beyond 90 years than the least-optimistic 25%, according to the 2022 study published in the Journal of the American Geriatrics Society.
Jeanne Case, 100, says she has taken a glass-half-full approach to life.
She plans to outlive her colon and skin cancers and keep enjoying swing music and Mexican food as long as she feels physically and mentally well.
A day in her life can include walking a mile, conversing with her writing group or noshing on fish tacos with friends. The Irvine, Calif., resident has always exercised but also enjoys indulgences like cheesecake and lemon bars.
“I try not to let stress bother me,” she says.
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Their careers spanned the personal computing, internet and smartphone waves. But some older workers see AI’s arrival as the cue to exit.
By Lauren Weber & Ray A. Smith
Tue, Apr 7, 2026 4 min
4 min
Luke Michel has already lived through two technology overhauls in his career, first desktop publishing in the 1980s and online publishing later on. But AI? He’s had enough.
So when his employer, the Dana-Farber Cancer Institute, made an early-retirement offer to some staff last year, the 68-year-old content strategist decided to speed up his exit. Before, he had expected to work a couple more years.
“The time and energy you have to devote to learning a whole new vocabulary and a whole new skill set, it wasn’t worth it,” he said.
It isn’t that he’s shunning artificial intelligence—he is learning Spanish with the help of Anthropic’s Claude. But, at this point, he’s less than eager to endure all the ways the technology promises to upend work.
“I just want to use it for my own purposes and not someone else’s,” he said.
After rising for decades and then hovering around 40% in the 2010s, the share of Americans over 55 years old in the workforce has slipped to 37.2%, the lowest level in more than 20 years.
The financial cushion of rising home equity and stock-market returns is driving some of the decline, economists and retirement advisers say.
But for some older professionals, money is only part of the equation.
They say they don’t want to spend the last years of their career going through the tumult of AI adoption, which has brought new tools, new expectations and a lot of uncertainty.
Many people retire when key elements of their work lives are disrupted at once, said Robert Laura , co-founder of the Retirement Coaches Association and an expert on the psychology of retirement.
“Maybe their autonomy is being challenged or changed, their friends are leaving the workplace, or they disagree with the company’s direction,” he said.
“When two or three of these things show up, that’s when people start to opt out.”
“AI is a big one,” he adds. “It disrupts their autonomy, their professionalism.”
Michel, whose work required overseeing and strategizing on website content, has been here before.
When desktop publishing arrived in the 1980s, he was a graphic designer using triangles and rubber cement.
The internet’s arrival changed everything again. Both developments required new skills, and he was energized by the challenge of learning alongside colleagues and peers.
It felt different this time around. “Your battery doesn’t hold a charge as long as it used to,” he said.
He would rather spend his energy volunteering, making art, going to operas and chairing the Council on Aging in North Andover, Mass., where he lives.
In an AARP survey last summer of 5,000 people 50 and over, 25% of those who planned to retire sooner than expected counted work stress and burnout as factors.
About half of those retired said they had left work at least partly because they had the financial security to do so.
In general, older Americans are less likely than younger counterparts to use AI, research shows.
About 30% of people from ages 30 to 49 said they used ChatGPT on the job, nearly double the share of those 50 and older, according to a 2025 Pew Research Center survey of more than 5,000 adults.
Baby boomers and members of Generation X also experienced the sharpest declines in confidence using AI technology, according to a ManpowerGroup survey of more than 13,900 workers in 19 countries.
“We as employers aren’t doing a good enough job saying (to older workers), we value the skills that you already have, so much so that we want to invest in you to help you do your job better,” says Becky Frankiewicz , ManpowerGroup’s chief strategy officer.
Jennifer Kerns’s misgivings about AI contributed to her departure last month from GitHub, where the 60-year-old worked as a program manager.
Coming from a family of artists, she said, it offends her that AI models train on the creative work of people who aren’t compensated for their intellectual property. And she worries about AI’s effect on people’s critical-thinking skills.
So she was dismayed when GitHub, a Microsoft-owned hosting service for software projects, began investing heavily in AI products and expecting employees to incorporate AI into much of their work. In employee-engagement surveys, the company had begun asking them to rate their AI usage on a scale of 1 to 5.
When it came time to write reports and reviews, colleagues would suggest that she use ChatGPT.
“I’d be like, ‘I have no idea how to use that and I have no interest in using AI to write anything for me,’” she said.
It would have been more prudent to work until she was closer to Medicare eligibility, she said. But by waiting until her children were out of college and some of her stock grants had vested, the math worked.
Her first act as a nonworking person: a solo trip to Scotland, where she took a darning workshop and learned how to repair sweaters.
“The opposite of AI,” she said.
Employers already under pressure to cut workers—such as in the tech industry—may welcome some of these retirements, said Gad Levanon , chief economist at Burning Glass Institute, which studies labor-market data.
“The more people retire, the fewer they have to let go,” he said.
Some of the savviest tech users are also balking at sticking around for the AI upheaval. Terry Grimm, who worked in IT for 40 years, retired from his senior software consultant role at 65 last May.
His firm had just been acquired by a bigger firm, which meant learning and integrating the parent company’s AI and other tech tools into his work.
Until then, Grimm expected he might work a couple more years, though he felt that he probably had enough saved to retire.
“I just got to the point where I was spending 40 hours at work and then 20 hours training and studying,” said Grimm, who has since moved with his wife from the Dallas area to a housing development on a golf course in El Dorado, Ark.
“I’m like, ‘I’ll let the younger guys do this.’”
